buddy of mine is actually running 315's on stock wheels with a 3 inch body lift.. only rubs at full turn on the control arms.. the 2500's should be able to clear 315's on stock wheels too with minor rubbing

 

i am. no problems other than the tire size causes the truck to be a little sluggish with stock 3.55 gears. its tolerable, but i turn o/d off for around town driving at about 45-50mph. if i don't it will shift up into overdrive and can't pull the next hill you come to.

 

i have 305/70/16 tires on mine and they only rub at full lock on the control arms.