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you want back pressure in your exhaust system in my opinion... if you open it up with a straight thru muffler & no cat, you'll loose mpg but gain upper end hp.
I believe it depends on your driving style and commute. If you do a lot of highway driving, low back pressure is better. If you do stop and go it is better to have some back pressure. Of the two, I say straight pipe is better. I am addicted to the sound