My Durango has a little over 50K miles on it. Three days ago I noticed a severe vibration in the steering wheel whenever I hit 20 mph on up. If I drop it down into 1st or 2nd, same vibration. I have the vibration if it is in 4 WD too. Is my transmission going or what? HELP!!!

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sounds more like a front wheel problem, either a tyre (check pressures), a flat spot (have you locked the breaks up lately), or wheel alignment out (have you hit anything).

I start there