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Yeah, usually on engines with individual coils, the coil is the root of any mis fire problems. But plugs are a lot cheaper so I would start by checking the plug and then like DakDan said, swap the coil with a working cylinder and see if the problem moves to that cylinder. Plugs and coils are really easy to do on a 4.7 so it shouldn't take long to figure it out unless its more of an electrical issue.
Switched coil from #3 cylinder to #1 problem followed giving a code of P0301. Installed a new coil, truck runs like new again.Thanks guys for the much needed help.
Good deal. At least it was a pretty easy fix and not a more complicated electrical issue. Those are my worst nightmare as they can be a pain to trace. Glad everything worked out.