Wilson/Easton is actually just off I-78/US-22. I-81 and I-78 intersect right here me, and 78 heads east towards Allentown/Bethlehem/Easton with US-22 paralleling it and 81 heads north towards Hazelton, Scranton and, eventually New York. I-78 is pretty flat, but I-81 (the route I ran) is pretty hilly.

 

81 isn't that bad i mean heading south its like a downhill pretty much on the way back up its like all up hill! but i've only traveled 81 through VA so it may be different in that neck of the woods!