Well, the tuner is not going to blow a transmission. Perhaps the extra power will condemn an already weak tranny, but not one in good shape. They can only increase line pressure and shift harshness so much without manually going into the trans and changing springs and such.
I run the 93 octane setting (mds on)with no problems. It doesn't shift much different than stock, so it's not a tuning issue. It does shift a bit quicker, but not harsh or firm.

SC is kissing butt now because they have some competition for the Hemi units now

I've never had any customer service issues with Diablosport. Quick answers and always helpful.